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. 2019 Sep 17;2019(9):CD003248. doi: 10.1002/14651858.CD003248.pub4

Chu 2011.

Methods Randomisd controlled trial
Participants Inclusion criteria
  • Pregnant women giving birth preterm – 24 to 32 weeks' gestation

  • No information as to whether included multiple births or not.

  • N = 38 babies


Exclusion criteria
Interventions Intervention: DCC
  • Clamping at 30 ‐ 45 secs

  • Mean clamping time 39.7 secs

  • N = 19 babies


Comparator: ECC
  • Immediate clamping

  • Mean clamping time 5.4 secs

  • N = 19 babies


Additional information
  • Gestational subgroup: < 32‐34 weeks' gestation

  • Resuscitation with cord intact: not available

  • Access to NICU: yes

  • Length of delay: 30‐45 secs

  • Baby placed: no information assume level with uterus and placenta

  • When uterotonic given; no information

  • UCM: n/a


Comparison 1
DCC with neonatal resuscitation after cord clamping vs ECC (subgroup by gestation)
Subgroup 1: < 32‐34 weeks' gestation
Comparison 2
DCC with neonatal resuscitation after cord clamping vs ECC (subgroup by type intervention)
Subgroup 1: DCC at < 1 min with baby level with uterus and placenta
Outcomes IVH, sepsis, anaemia, and hyperbilirubinaemia
Notes Setting: Toronto, Canada
Dates: not reported
Trial funding source: not reported
Declaration of interest: not reported
Further information:
  • Conference abstract only.

Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk No information
Allocation concealment (selection bias) Unclear risk No information
Blinding of participants and personnel (performance bias) 
 All outcomes High risk No information. Clinicians at birth likely to be unblinded.
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk No information
Incomplete outcome data (attrition bias) 
 All outcomes Low risk No losses reported
Selective reporting (reporting bias) Unclear risk We did not assess trial protocol
Other bias Unclear risk Compliance: 1 protocol violation ‐ not told which group. No other information. Conference abstract only.