Ranjit 2015.

Methods	Randomised controlled trial
Participants	Inclusion criteria Neonates born between 30 0/7 and 36 6/7 weeks of gestation N = 100 babies Exclusion criteria Mothers with Rhesus negative blood group and monoamniotic – monochorionic twins
Interventions	Intervention: DCC Cord was clamped more than 2 mins after the birth of the baby. Until the cord was clamped, the baby was placed covered on the mother’s abdomen in case of vaginal births or on the mother’s thigh in case of CSs. In babies needing resuscitation at birth, immediate cord clamping was practiced irrespective of group allocation. N = 50 babies (6 were excluded because they needed resuscitation) ‐ analysed 44 Comparator: ECC Cord was clamped immediately after birth of the infant, the standard practice at authors’ institution. N = 50 babies Additional information Gestational subgroup: mixed gestation Resuscitation with cord intact: not available Access to NICU: yes Length of delay: > 2 mins Baby placed: on mother's abdomen at vaginal births and on mother's thigh at caesarean Uterotonic: no information UCM: n/a Comparison 1 DCC with neonatal resuscitation after cord clamping vs ECC (subgroup by gestation) Subgroup 3: mixed gestation Comparison 2 DCC with neonatal resuscitation after cord clamping vs ECC (subgroup by type intervention) Subgroup 5: DCC at > 2 mins with baby level with uterus and placenta
Outcomes	Primary Hct and serum ferritin levels at 6 weeks of age Secondary Hct on day 1; anaemia, polycythaemia, significant jaundice, duration of phototherapy; need for blood transfusions; PDA; RDS; NEC; transient tachypnoea of newborn (TTNB); sepsis; IVH; hypoglycaemia; apnoea; shock; hypoxic ischaemic encephalopathy (HIE); acute kidney injury (AKI) and death. Definitions Significant jaundice was defined as need for phototherapy based on AAP 2004 policy statement for babies > 35 weeks (6) and phototherapy guidelines for very low birthweight infants (7). Anemia and polycythaemia on day 1 were defined as Hct < 45% and > 65% respectively.
Notes	Setting: tertiary care hospital in South India Dates: May 2010 to November 2010 Declaration of interest: no conflict of interest. Trial funding source: quote: "Role of funding source ‐ None" Further information Reported sepsis and unclear of this is late sepsis, but we used the data. Reported transfusion of packed cells and we used this data under 'Blood transfusion'. Reported exclusive breastfeeding: 100% for DCC and 89.5% for ECC. We are writing to the authors to ask whether any of the 6 babies excluded from the DCC group (because they needed resuscitation) had died. We have included the data on death in out data and analysis.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Qquote: “…based on computer generated random numbers.”
Allocation concealment (selection bias)	Low risk	Quote: “Allocation concealment was achieved by sequentially numbered opaque sealed envelopes containing the codes for intervention”
Blinding of participants and personnel (performance bias) All outcomes	High risk	It is not possible to blind clinicians nor women.
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	There is no information as to whether there was any attempt to blind outcome assessment.
Incomplete outcome data (attrition bias) All outcomes	High risk	6 babies (12%) randomised to DCC group were excluded from the study as they did not receive the intervention due to the need for resuscitation. None were excluded from the ECC group, yet 5 died in the ECC group and no deaths were reported in the DCC group, but there is no information on the 6 who were excluded ‐ it is important to know how many of these died. 4 in the ECC group and 3 in the DCC group were lost for follow‐up. Total exclusion DCC 9/50 (18%) ICC 4/50 (8%). Overall 13% exclusions, but uneven.
Selective reporting (reporting bias)	Unclear risk	We did not assess the trial protocol.
Other bias	Unclear risk	Baseline characteristics were similar but they excluded 6 babies from DCC because they needed resuscitation.