Table 8. Stained area percent for the expression of TNF-α, p53, caspase-3 and Bcl-2 in kidney of normal, diabetic control and diabetic groups treated with enalapril, paricalcitol and their mixture.
| TNF-α | p53 | Caspase-3 | Bcl-2 | |
|---|---|---|---|---|
| Normal | 0.096±0.022b | 0.654±0.140c | 0.342±0.169c | 8.637±0.511b |
| Diabetic control | 2.916±0.328a | 14.774±2.338a | 5.082±1.118a | 1.148±0.107c |
| Diabetic treated with Enalapril | 0.195±0.070b | 0.553±0.167c | 0. 330±0.010c | 7.678±0.747b |
| Diabetic treated with Paricalcitol | 0.518±0.170b | 5.062±0.788b | 2.844±0.365b | 8.448±1.335b |
| Diabetic treated with Enalapril and Paricalcitol | 0.133±0.413b | 0.701±0.171c | 0.194±0.042c | 15.121±3.518a |
| F-probability | P<0.001 | P<0.001 | P<0.001 | P<0.01 |
| LSD at 5% level | 0.535 | 3.498 | 1.675 | 5.455 |
| LSD at 1% level | 0.761 | 4.976 | 2.382 | 7.759 |
- Data are expressed as mean ± SE. Number of replicates in each group is 3.
- Means, which share the same superscript symbol(s) are not significantly different.