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. 2019 Aug 30;15(8):e1007978. doi: 10.1371/journal.ppat.1007978

Fig 3. The D-peptides stabilize soluble CsgA and inhibit fibrillation.

Fig 3

The effect of D-peptide inhibitors on CsgA fibrillation at 5:1 molar ratios, as quantified based on CsgA ability to migrate on a 15% SDS-PAGE (exemplified in S12 Fig). CsgA incubated with ANK6 and DB3DB3 showed a prolonged soluble state, suggesting inhibition of the rapid formation of SDS-insoluble fibrils. The graph represents three experimental repeats. The experiments were repeated at least three times on different days, all giving similar results.