Table 4.
Competing Risks Cause Specific Adjusted Hazard Ratios for Mode of Transition From pre-ART Care in Tanzania.a
| Characteristic | Started ART, aHR (95% CI) | Died, aHR (95% CI) | Lost to follow-up, aHR (95% CI) | Transferred, aHR (95% CI) |
|---|---|---|---|---|
| Sex | ||||
| Female | 1.0 | 1.0 | 1.0 | 1.0 |
| Male | 1.01 (1.00-1.03) | 1.49 (1.40-1.58) | 1.14 (1.10-1.19) | 1.15 (1.09-1.20) |
| Age in years | ||||
| 15-25 | 1.0 | 1.0 | 1.0 | 1.0 |
| 26-35 | 0.73 (0.70-0.76) | 0.67 (0.58-0.78) | 1.42 (1.30-1.54) | 1.01 (0.92-1.12) |
| 36-45 | 0.91 (0.88-0.94) | 0.83 (0.75-0.92) | 1.11 (1.03-1.19) | 0.90 (0.83-0.97) |
| 46-55 | 1.04 (1.01-1.07) | 0.84 (0.75-0.93) | 0.92 (0.85-0.99) | 0.85 (0.79-0.93) |
| > 55 | 1.08 (1.05-1.12) | 0.85 (0.76-0.96) | 0.82 (0.76-0.90) | 0.83 (0.75-0.91) |
| CD4 count/mm3 | ||||
| ≤ 50 | 1.0 | 1.0 | 1.0 | 1.0 |
| 51-100 | 0.90 (0.88-0.93) | 0.62 (0.53-0.72) | 0.94 (0.82-1.07) | 0.98 (0.84-1.15) |
| 101-200 | 0.89 (0.86-0.91) | 0.40 (0.35-0.47) | 0.76 (0.67-0.86) | 0.86 (0.75-0.99) |
| 201-350 | 0.39 (0.38-0.40) | 0.32 (0.27-0.37) | 1.04 (0.94-1.16) | 1.07 (0.95-1.21) |
| > 350 | 0.10 (0.09-0.10) | 0.22 (0.19-0.25) | 1.18 (1.07-1.30) | 1.17 (1.05-1.31) |
| Missing | 0.24 (0.24-0.25) | 0.99 (0.90-1.09) | 2.55 (2.34-2.79) | 1.51 (1.36-1.68) |
| Opportunistic Infections | ||||
| Tuberculosis | ||||
| No | 1.0 | 1.0 | 1.0 | 1.0 |
| Yes | 0.72 (0.65-0.80) | 0.95 (0.72-1.26) | 1.06 (0.89-1.26) | 1.15 (0.90-1.46) |
| Cryptococcal disease | ||||
| No | 1.0 | 1.0 | 1.0 | 1.0 |
| Yes | 2.08 (1.42-3.05) | 3.40 (1.61-7.15) | 0.20 (0.03-1.45) | 0.50 (0.07-3.53) |
| PCP | ||||
| No | 1.0 | 1.0 | 1.0 | 1.0 |
| Yes | 1.75 (1.55-1.97) | 1.24 (0.86-1.80) | 0.46 (0.32-0.65) | 0.94 (0.63-1.40) |
| Other | ||||
| No | 1.0 | 1.0 | 1.0 | 1.0 |
| Yes | 0.94 (0.92-0.96) | 1.36 (1.25-1.48) | 1.16 (1.10-1.22) | 1.10 (1.02-1.17) |
| Enrollment year | ||||
| 2004 | 1.30 (1.10-1.55) | 3.08 (2.01-4.70) | 3.27 (2.12-5.05) | 1.48 (0.91-2.41) |
| 2005 | 1.02 (0.98-1.07) | 2.22 (1.90-2.59) | 9.66 (8.94-10.98) | 1.74 (1.52-1.99) |
| 2006 | 0.90 (0.87-0.94) | 2.25 (1.97-2.57) | 9.86 (8.73-11.13) | 1.81 (1.62-2.03) |
| 2007 | 0.88 (0.85-0.91) | 1.71 (1.50-1.95) | 6.70 (5.94-7.56) | 1.67 (1.50-1.86) |
| 2008 | 0.95 (0.92-0.99) | 1.47 (1.28-1.68) | 3.30 (2.91-3.73) | 1.95 (1.76-2.17) |
| 2009 | 0.95 (0.92-0.98) | 1.26 (1.10-1.44) | 2.35 (2.07-2.67) | 1.75 (1.57-1.94) |
| 2010 | 0.99 (0.96-1.03) | 0.90 (0.77-1.04) | 1.82 (1.59-2.08) | 1.20 (1.07-1.35) |
| 2011 | 1.0 | 1.0 | 1.0 | 1.0 |
Abbreviations: aHR, adjusted hazard ratios; ART, antiretroviral therapy; CI, confidence interval; PCP, Pneumocystis jiroveci pneumonia.
an = 117 385.