Table 1.
Sample Characteristics at Index.
| Variables | Non-PPI Control, N = 5718 | PPI, N = 329 | P Value |
|---|---|---|---|
| Age at index (years) | 51.08 (10.151) | 55.01 (9.428) | <.001 |
| Race | |||
| Black | 2484 (43%) | 127 (39%) | <.001 |
| Other/Unknown | 1480 (26%) | 68 (21%) | |
| White | 1754 (31%) | 134 (41%) | |
| Sex | |||
| Female | 127 (2%) | 11 (3%) | .021 |
| Male | 4976 (87%) | 297 (90%) | |
| Unknown | 615 (11%) | 21 (6%) | .021 |
| Viral suppression | |||
| No | 1056 (18%) | 67 (20%) | .017 |
| Unknown | 2550 (45%) | 166 (50%) | |
| Yes | 2112 (37%) | 96 (29%) | |
| Charlson comorbidity | 1.01 (1.564) | 2.66 (2.851) | <.001 |
| Drug/alcohol | 2200 (38%) | 154 (47%) | .003 |
| Index Mg (mg/dL) | 2.06 (0.279) | 1.99 (0.278) | <.001 |
| Index Mg <1.7 mg/dL | 325 (6%) | 31 (9%) | .007 |
| Year | 2007.3 (3.554) | 2007.39 (3.068) | .649 |
| Regimena | |||
| STR | 1299 (23%) | 65 (20%) | .237 |
| MTR: PI | 2952 (52%) | 150 (46%) | .038 |
| MTR: NNRTI | 1497 (26%) | 120 (36%) | <.001 |
| MTR: ISTI | 277 (5%) | 24 (7%) | .063 |
Abbreviations: ISTI, integrase strand transfer inhibitors; MTR, multiple-tablet regimen; NNRTI, non-nucleoside reverse transcriptase inhibitor; PI, protease inhibitor; PPI, proton pump inhibitors; STR, single-tablet regimen.
aRegimen percentages do not add up to 100% due to regimen switches during the study.