Table 3.
Risk of Hypomagnesemia (Magnesium < 1.7 mg/dL).
| Variables | HRa | 95% CI |
|---|---|---|
| PPI 80%-100% PDC | 3.1624 | 2.56-3.90 |
| Age (18-25 years reference) | ||
| 26-35 | 0.9731 | 0.23-4.07 |
| 36-45 | 1.3318 | 0.33-5.39 |
| 46-55 | 1.4434 | 0.36-5.83 |
| 56-65 | 1.9677 | 0.49-7.98 |
| 66-75 | 1.694 | 0.41-7.04 |
| 75+ | 3.779 | 0.88-16.31 |
| Sex (female reference) | ||
| Male | 0.7865 | 0.50-1.23 |
| Unknown | 0.7951 | 0.48-1.30 |
| Race (black reference) | ||
| Other/unknown | 0.7977 | 0.66-0.97 |
| White | 0.6528 | 0.56-0.76 |
| Charlson comorbidity | 1.1932 | 1.16-1.23 |
| Virally suppressed (no reference) | ||
| Unknown | 0.7691 | 0.65-0.90 |
| Yes | 0.5546 | 0.46-0.67 |
| Drug/alcohol | 1.4215 | 1.24-1.63 |
| Year | 0.9405 | 0.92-0.96 |
Abbreviations: HR, hazard ratio; PDC, proportion of days covered; PPI, proton pump inhibitors.
aModel is stratified on indicator for index magnesium (<1.7 mg/dL yes/no); N: 6047; No. Events: 901; Ho: Proportional Hazards holds: χ2 = 23.02, P value = .11.