Table 2.

Pharmacokinetic parameters of LBL-007 antibody levels in monkeys.

		t1/2	C5min	AUClast	AUC0-∞	V	CL	MRTlast
dose (mg/kg)		(h)	(µg/mL)	(h*µg/mL)	(h*µg/mL)	(mL/kg)	(mL/h/kg)	(h)
3	Mean	275.31	73.22	9013.81	11364.48	109.27	0.27	229.32
	SD	13.87	17.27	2327.64	2970.21	33.84	0.07	5.17
10	Mean	335.31	194.4	26601.72	34144.9	148.28	0.31	224.5
	SD	36.9	53.34	9867.22	12139.57	37.13	0.11	5.52
30	Mean	193.52	616.15	63570.08	69937.95	119.44	0.43	203.43
	SD	31.95	122.23	934.48	3042.52	14.57	0.02	2.54

Pharmacokinetic parameters were calculated using a non-compartmental analysis. T_1/2, half-life; C_5min, concentration of 5 min; AUC, The area under the concentration versus time curve; V, apparent volume of distribution; CL, clearance; MRT, Mean Residence Time.