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Relationship between in vitro lens/buffer partition coefficient (Kp) (mean ± SD, n = 5–10) and compound lipophilicity (log D7.4 and PSA) for all of the studied compounds and a series of β-blockers nadolol, atenolol, carteolol, pindolol, betaxolol, and propranolol. The Kp values were calculated by using both the image-based distribution volume and the total anatomical volume of the lens.
