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. 2019 Mar 25;74(10):1628–1636. doi: 10.1093/gerona/glz084

Table 3.

Change in Body Composition (Weight, Fat, Muscle Mass) at Week-4 Testing

Variable All sample (n = 63) Placebo (n = 10) Whey protein (n = 11) Rehabilitation + placebo (n = 13) Rehabilitation + protein (n = 12) Testosterone (n = 17) All active intervention groups (n = 53) p-Value (across groups) p-Value (placebo vs. interventions)
Weight, kg 0.290 ± 1.74 0.380 ± 1.27 0.273 ± 1.93 0.777 ± 2.26 0.992 ± 1.21 –0.618 ± 1.49 0.274 ± 1.74 .38 .67
 Loss 24 (38) 3 (30) 6 (55) 4 (31) 1 (8) 10 (59) 21 (40)
 No change 2 (3) 1 (10) 0 (0) 0 (0) 0 (0) 1 (6) 1 (2)
 Gain 37 (59) 6 (60) 5 (45) 9 (69) 11 (92) 6 (35) 31 (58)
Fat, kg –0.056 ± 1.23 –0.110 ± 0.77 0.108 ± 1.50 –0.140 ± 1.42 0.328 ± 1.27 –0.338 ± 1.13 –0.046 ± 1.23 .69 .98
 Loss 33 (52) 5 (50) 5 (45) 8 (62) 6 (50) 9 (53) 28 (53)
 No change 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0)
 Gain 30 (48) 5 (50) 6 (55) 5 (38) 6 (50) 8 (47) 25 (47)
Muscle mass, kg 0.331 ± 1.53 0.493 ± 0.92 0.087 ± 1.60 0.905 ± 1.84 0.641 ± 1.59 –0.265 ± 1.40 0.300 ± 1.53 .27 .72
 Loss 25 (40) 2 (20) 5 (45) 4 (31) 4 (33) 10 (59) 23 (43)
 No change 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0)
 Gain 38 (60) 8 (80) 6 (55) 9 (69) 8 (67) 7 (41) 30 (57)
Appendicular lean mass, kg –0.106 ± 0.99 –0.212 ± 0.77 –0.065 ± 1.04 0.317 ± 1.10 0.001 ± 1.10 –0.469 ± 0.98 –0.086 ± 0.99 .29 .59
 Loss 37 (59) 7 (70) 6 (55) 6 (46) 5 (42) 13 (76) 30 (57)
 No change 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0)
 Gain 26 (41) 3 (30) 5 (45) 7 (54) 7 (58) 4 (24) 23 (43)

Note: All data are mean ± standard deviation or number of participants (percentage). A positive number is an increase in mass.