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. 2019 Jun 11;111(9):903–915. doi: 10.1093/jnci/djz105

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Figure 1. — Networks for A) overall survival (OS) and B) disease-free survival (DFS). The width of the lines is proportional to the number of trials comparing each pair of treatments, and the size of each node is proportional to the number of randomly assigned participants (sample size). BCS+ALND = breast-conserving surgery+axillary lymph node dissection. BCS+ALND+RT = breast-conserving surgery+axillary lymph node dissection+radiotherapy. BCS+ANS+RT = breast-conserving surgery+axillary node sample+radiotherapy. BCS+SLNB = breast-conserving surgery+sentinel lymph node biopsy. BCS+SLNB+ART+RT = breast-conserving surgery+ sentinel lymph node biopsy+axillary radiotherapy +radiotherapy. BCS+SLNB+IORT = breast-conserving surgery+sentinel lymph node biopsy+Intraoperative radiotherapy. BCS+SLNB+RT = breast-conserving surgery+sentinel lymph node biopsy+radiotherapy. M = mastectomy. M+ALND = mastectomy+axillary lymph node dissection. M+ALND+RT = mastectomy+axillary lymph node dissection+radiotherapy. M+RT = mastectomy+radiotherapy.