Fig. 6.

CL-PE cluster lipid pathways altered in CKD progression. (A) Stages 2 and 3 in CPROBE; (B) stages 4 and 5 in CPROBE; (C) non-progressor in CRIC; (D) progressor in CRIC. Blue edges are more likely to be present in early-stage disease (CPROBE) and in non-progressors (CRIC). Pink edges are more likely to be present in late-stage CKD (CPROBE) and in progressors (CRIC). Black edges are equally likely to be present in both conditions. CPROBE, Clinical Phenotyping Resource and Biobank Core; CRIC Chronic Renal Insufficiency Cohort; CL, cardiolipin; PE, phosphatidylethanolamine