Table 1.

Reason categories for drug discontinuation

DDC reason category	Scope of coverage	Example
Adverse_Event	Adverse drug events leading to a DC, such as side effects, contraindication, toxicity, drug interactions, etc.	1. Her Bactrim was discontinued and her rash is slowly resolving.
		2. I have asked him to discontinue his Percocet as he is exceeding the Tylenol limitations per day.
Drug_Modification	Non-AE related drug modification demanded by physician, such as drug switch due to ineffectiveness, or procedure accommodation, etc.	1. He received a couple of doses in mid [**Date**] and treatment with Rituxan was stopped when he had obvious progression at that point.
		2. She is about to undergo a herniorrhaphy, so I have written instructions for how to transition from Suboxone to morphine.
Non_Medical	This category covers natural stop cases (eg, drug prescribed is finished or not needed) or patient self-discontinuation (eg, nonadherence or formulary change)	1. The patient received 6 courses of cyclophosphamide, vincristine, and prednisone completed [**Date**].
		2. She had refused Procrit shots of late.
Unknown	No reason is mentioned	N/A