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. 2018 Dec 17;80(5):540–546. doi: 10.1055/s-0038-1676628

Table 3. Summary of other bevacizumab studies.

Article Sample size Dose Median treatment time Response
Plotkin et al 8 10 patients 5 mg/kg every 2 weeks 12 months 90% with reduction in tumor size
Plotkin et al 9 31 patients 5 mg/kg every 2 weeks 14 months Freedom from progression in 88% by 1 year and 67% by 2 years
Alanin et al 10 12 patients First 6 months: 10 mg/kg every 2 weeks Maintenance:
15 mg/kg every 3 weeks
22 months Reduction in tumor volume in 88%
Current study 7 patients First 6 months:
10 mg/kg every 2 weeks
Maintenance:
5 mg/kg every 3 weeks
33 months Freedom from linear and volumetric progression, respectively:
1 year: 90%, 100%
2 years: 79%, 88%
3 years: 53%, 70%