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. Author manuscript; available in PMC: 2020 Dec 16.
Published in final edited form as: Behav Brain Res. 2019 Aug 1;375:112116. doi: 10.1016/j.bbr.2019.112116

Figure 3. Spatial navigation circuit.

Figure 3.

[59, 96] Overlaid onto the circuit are the significant changes in functional brain activation between LEARNERS and CONTROLS during retrieval of spatial memory. Shading indicates a significant increase (gray) or decrease (black) in regional cerebral perfusion (P<0.05 for >100 significant, contiguous voxels). No shading indicates no significant change in perfusion. Circuit has been adapted from Bird (2008) and Aggleton (2000), with lines between boxes delineating known major neuronal pathways connecting each region.[59, 96] Abbreviations: ATN (anterior thalamic nucleus), Au (auditory cortex), HPC (hippocampus, posterior CA1–3), I (insular cortex), MD (medial dorsal thalamic n.), OFC (orbitofrontal cortex), Pir (piriform cortex), PostRh (postrhinal cortex), PRh (perirhinal cortex), PrL (prelimbic cortex), RS (retrosplenial cortex), Septal nucleus (medial), Sub (subiculum).