Table 3.

Cost base input values, ranges, and standard deviations used for sensitivity analyses

Age group (years)	Base value	Range	Standard deviation	References
Cost per HZ case, $
50–59	264	211.20, 316.80	26.94	Friesen et al. [12]; Ontario calculationsa
60–64	264	211.20, 316.80	26.94
65–69	301	240.80, 361.20	30.71
70–79	301	240.80, 361.20	30.71
≥ 80	301	240.80, 361.20	30.71
Cost per PHN case, $
50–59	921	571.02, 1270.98	178.56	Friesen et al. [12]; Ontario calculationsa
60–64	921	571.02, 1270.98	178.56
65–69	1639	571.02, 1270.98	317.77
70–79	1639	571.02, 1270.98	317.77
≥ 80	1639	1016.18, 2261.82	317.77
Vaccine cost, RZV, $
All age groups	122	115.90, 128.10	–	IMS
Vaccine cost, ZVL, $
All age groups	176.77	–	–	IMS
Vaccine administration, $
First dose	4.50	4.50, 9.60		Ontario calculationsa
Second dose	9.60	4.50, 9.60
Costs due to AEs per vaccinated individual, RZV, $
50‒59	2.88	1.44, 4.32	0.734	Ontario calculationsa
60‒64	2.62	1.31, 3.93	0.668
65‒69	2.89	1.45, 4.34	0.737
70‒79	2.81	1.41, 4.22	0.716
≥ 80	2.81	1.41, 4.22	0.716
Costs due to AEs per vaccinated individual, ZVL, $
50‒59	1.70	0.85, 2.55	0.433	Ontario calculationa
60‒64	1.70	0.85, 2.55	0.433
65‒69	1.70	0.85, 2.55	0.433
70‒79	1.70	0.85, 2.55	0.433
≥ 80	1.70	0.85, 2.55	0.433

All $ refer to Canadian dollars

AE adverse event, HZ herpes zoster, PHN postherpetic neuralgia, RZV adjuvanted recombinant zoster vaccine, ZVL zoster vaccine live

^aDerived from Ontario Ministry of Health and Long-term Care (MOHLTC) fee schedules and Ontario Case Costing Initiative (OCCI)