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. 2019 Sep 17;9:13445. doi: 10.1038/s41598-019-49937-w

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Early but not late granulopoiesis is induced by EBV infection in the bone marrow. (A) May-Grunwald Giemsa stain of hCD66b⁺ cells which were isolated from mice BM. Blast (*) and matured cells were observed (x600). White arrows show band neutrophils. (B) Ratio of band/segmented neutrophils in isolated hCD66b⁺ cells of BM were compared between infected (n = 3) and uninfected (n = 3) mice. Significant difference were not detected (Not significant; N.S.). (C) Frequency of hCD66b⁺ myeloid progenitors in BM were compared with infected and uninfected mice. EBV infected mice BM showed significantly increased progenitors. Data mean ± SD. ***p < 0.005.