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ZIKV RNA levels in the MEFs and neurons isolated from WT and ZBP1−/− mice. (A–D) Cells were infected with ZIKV MR766 or ZIKV PRVABC59 at a MOI of 1. Total RNA was extracted from cell lysates and ZIKV RNA was measured by qRT-PCR (expressed as genome copies/μg of RNA). Error bars represent SEM (three independent experiments conducted in duplicate), *p < 0.05, **p < 0.001.
