TABLE 1.
Hospital name | Patient no. | Age (years) | Sex | Disease duration | OMDS at baseline | mPSL dose (mg/day) | PSL dose from after pulse therapy until year 2 (mg/day) |
Fukuoka University Hospital (FUH) | 1 | 61 | F | 3 months | 6 | 1000 | 0.0 |
2 | 71 | F | 8 months | 9 | 1000 | 50.0 → 10.0 | |
3 | 71 | F | 6 months | 4 | 1000 | 0.0 | |
4 | 72 | F | 2 years | 5 | 1000 | 0.0∗ | |
5 | 48 | F | 16 years | 4 | 1000 | 0.0 | |
6 | 67 | F | 4 years | 4 | 1000 | 20.0 → 5.0 | |
7 | 68 | F | 9 years | 4 | 1000 | 0.0 | |
St. Marianna University Hospital (SMUH) | 8 | 58 | F | 1 year | 6 | 1000 | 20.0 → 10.0 |
9 | 53 | M | 2 years | 6 | 250 | 40.0 → 7.0 | |
10 | 67 | F | 4 years | 3 | 500 | 15.0 → 2.0 | |
11 | 33 | F | 17 years | 6 | 500 | 20.0 → 5.0 | |
12 | 67 | F | 19 years | 8 | 500 | 30.0 → 8.0 | |
13 | 62 | F | 10 years | 6 | 1000 | 25.0 → 7.0 | |
SMUH | 14 | 71 | F | 18 years | 5 | 0 | N/A |
15 | 71 | F | 13 years | 5 | 0 | N/A | |
16 | 59 | F | 1 year | 1 | 0 | N/A | |
17 | 64 | F | 4 years | 4 | 0 | N/A | |
18 | 45 | F | 10 years | 4 | 0 | N/A | |
Hospital name | Patient no. | Age (years) | Sex | Disease duration | OMDS at baseline | PSL dose (mg/day) | |
FUH | 19 | 58 | F | 3 years | 3 | 5 | |
SMUH | 20 | 59 | F | 12 years | 5 | 3 | |
21 | 64 | F | 18 years | 5 | 3 | ||
22 | 67 | F | 4 years | 4 | 5 |
OMDS, osame motor disability score; mPSL, methylprednisolone; PSL, prednisolone; F, female; M, male; N/A, not applicable. ∗Patient no. 4 received oral prednisolone therapy from 3 months after treatment because of high levels of CXCL10 and neopterin (Figure 3).