Table 3.
Clinicopathologic characteristics of 76 ACC patients from TCGA database.
| Characteristics | Entire cohort (N = 76) |
|---|---|
| N (%) | |
| Age, years | |
| ≤57 | 54 (71.1) |
| >58 | 22 (28.9) |
| Gender | |
| Male | 30 (39.5) |
| Female | 46 (60.5) |
| Germline testing performed | |
| Present | 12 (18.2) |
| Absent | 54 (81.1) |
| Laterality | |
| Left | 42 (55.3) |
| Right | 34 (44.7) |
| pT stage | |
| T1 – T2 | 50 (65.8) |
| T3 – T4 | 26 (34.2) |
| pN stage | |
| N0 | 68 (89.5) |
| N1 | 8 (10.5) |
| M stage | |
| M0 | 62 (81.6) |
| M1 | 14 (18.4) |
| Pathologic stage | |
| I – II | 46 (60.5) |
| III – IV | 30 (39.5) |
| Histological type | |
| Myxiod | 1 (1.3) |
| Oncocytic | 3 (3.9) |
| Usual | 72 (94.7) |
| Mitotic rate | |
| ≤5/50 HPF | 26 (38.8) |
| >5/50 HPF | 41 (61.2) |
| Invasion of tumor capsule | |
| Absent | 30 (42.9) |
| Present | 40 (57.1) |
| Sinusoid invasion | |
| Absent | 34 (58.6) |
| Present | 24 (41.4) |
| Necrosis | |
| Absent | 17 (23.9) |
| Present | 54 (76.1) |
| Weiss score | |
| ≤3 | 17 (22.0) |
| >4 | 47 (78.0) |
| Persistent distant metastasis | |
| Absent | 56 (73.7) |
| Present | 20 (26.3) |
ACC, adrenocortical carcinoma; TCGA, the Cancer Genome Atlas; HPF, high power field.