Figure 2. TDP-43 KO affects the morphology of multiple organelles.

(A, B, C, D, E) Representative confocal immunofluorescence images with nuclear pore (Nup62, panels [A]), Golgi (GM130, panels [B]), early endosome (EEA1, panels [C]), late endosome/lysosome (LAMP1, panels [D]), and mitochondria (cytochrome c, panels [E]) antibodies from cells of the indicated genotypes. Representative images are presented from the analysis of 2–3 biological replicates for each condition. Scale bar = 10 μm.