Table 3. The relationships among immune and pathological biomarkers.
Characteristic | OX40 expression on TILs | P value | |
---|---|---|---|
Negative | Positive | ||
OX40 expression on tumor | 0.028 | ||
Negative | 65 | 60 | |
Positive | 3 | 11 | |
PD-L1 expression on tumor | 0.006 | ||
Negative | 62 | 52 | |
Positive | 6 | 19 | |
OX40L expression on tumor | 0.074 | ||
Negative | 55 | 48 | |
Positive | 13 | 23 | |
PD-1 expression | 0.0001 | ||
Negative | 51 | 28 | |
Positive | 17 | 43 | |
TILs in the tumor microenvironment | 0.001 | ||
Negative | 41 | 22 | |
Positive | 27 | 49 | |
PD-L1 expression on TILs | 0.0001 | ||
Negative | 57 | 32 | |
Positive | 11 | 39 | |
Pathology types | 0.042 | ||
Non-adenocarcinoma | 43 | 56 | |
Adenocarcinoma | 25 | 15 |
PD-1, program death-1; PD-L1, program death-ligand 1; TILs, tumor infiltrating lymphocytes.