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. 2019 Aug;8(4):401–412. doi: 10.21037/tlcr.2019.08.13

Figure 3.

Figure 3

A 67-year-old male diagnosed with KRAS mutated lung adenocarcinoma. (A) DESCT 70 keV image showing a solid nodule in the middle lobe of the right lung, with a CT value at 70 keV of 49.71 HU. (B) Effective-Z material-decomposition image showing an Effective Z of the nodule of 8.02. (C) The graph shows the spectral Hounsfield unit curve of the nodule, with a λHU slope of 0.82. (D) Molecular pathological results showing KRAS mutations. (E) KRAS mutation prediction according to various significant factors and their combination (with AUC =0.832). DESCT, dual-energy spectral computed tomography; Effective-Z, effective atomic number; λHU slope, spectral Hounsfield unit curve; ROC, receiver operating characteristic; AUC, area under curve.