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. 2019 Sep 11;10:614. doi: 10.3389/fendo.2019.00614

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Copyright © 2019 Haahr, Dosouto, Alviggi, Esteves and Humaidan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Online calculator to determine the minimum number of mature oocytes required to obtain at least one euploid blastocyst for transfer in infertile patients undergoing IVF/ICSI cycles. The figure shows how the online calculator can be used in an office-based setting. Pre-treatment, clinicians should input the patient age and the sperm source to be used for IVF/ICSI. If the option “Testicle” is marked, then the type of azoospermia should be also defined. The probability of success is set by the user and indicates the chance of having ≥1 euploid blastocyst when the predicted number of mature oocytes is achieved. Its complement is the risk, that is, the chance of having no (zero) euploid blastocysts when the predicted number of oocytes is achieved. Once the button “calculate” is pressed, a text box will pop-up on the right side of the screen, indicating the predicted minimum number of mature oocytes needed for obtaining at least one euploid blastocyst, with its 95% confidence interval (reprinted with permission of the author).