FIGURE 1.

[¹⁸F]-THK5351 tracer uptake. (A) High midbrain uptake in axial and sagittal slices allows visual discrimination of the PSP patient group from other patient groups. Significantly higher [¹⁸F]-THK5351 uptake in the diencephalon was detected in PSP patients compared to PD and MSA-C patients. In contrast, in MSA-C patients, but not in MSA-P patients, [¹⁸F]-THK5351 uptake was especially high in the pons and cerebellar deep white matter. (B) Tracer uptake in the midbrain, pons, diencephalon, and cerebellar deep white matter. ^∗ indicates significant differences.