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. 2019 Aug 22;24(17):3046. doi: 10.3390/molecules24173046

Figure 3.

Figure 3

Gene Set Enrichment Analysis (GSEA) suggested that the combination of Bevacizumab and Temozolomide activated genes related to immunocyte migration (myeloid leukocyte migration, leukocyte chemotaxis, and lymphocyte migration/ chemotaxis), but suppressed genes related to the cell cycle (DNA replication, mitotic recombination, chromosome condensation, and DNA strand elongation) in IDH1-mutant U87 cells.