Table 3.
Blood biochemistry of healthy dogs (control group), dogs with mitral regurgitation ACVIM Class Cc (heart group), and the kidney group (azotemic dogs). Average ± standard deviation.
| Variables | Control Group | Heart Group | Kidney Group | p Value |
|---|---|---|---|---|
| Urea mmol/L | 5.20 ± 1.54 | 9.63 ± 10.51 | 23.08 ± 15.63 | 0.012 * |
| Creatinine µmol/L | 105.88 ± 44.90 | 85.59 ± 27.50 | 295.83 ± 140.35 | 0.001 *# |
| SDMA µg/dL | 10.75 ± 1.39 | 14.10 ± 5.40 | 25.70 ± 5.70 | 0.001 *# |
| Cyst C mg/L | 0.93 ± 0.14 | 1.50 ± 0.60 | 2.28 ± 1.15 | 0.002 *^ |
| Total protein g/L | 59.00 ± 6.07 | 63.10 ± 4.34 | 58.50 ± 8.14 | NS |
| Albumin g/L | 30.88 ± 2.47 | 32.64 ± 3.26 | 28.98 ± 5.32 | NS |
| Mg mmol/L | 0.78 ± 0.10 | 0.79 ± 0.13 | 0.88 ± 0.09 | NS |
| Na mmol/L | 143.55 ± 1.91 | 145.66 ± 2.79 | 145.08 ± 4.25 | NS |
| K mmol/L | 4.57 ± 0.33 | 4.72 ± 0.47 | 4.74 ± 0.31 | NS |
| Cl mmol/L | 110.16 ± 0.64 | 108.30 ± 3.37 | 114.12 ± 4.76 | 0.004 # |
| Ca2+ mmol/L | 1.31 ± 0.06 | 1.29 ± 0.07 | 1.34 ± 0.26 | NS |
| Fe µmol/L | 32.64 ± 7.27 | 24.42 ± 5.99 | 28.84 ± 1.29 | 0.048 ^ |
| CRP mg/L | 1.74 ± 0.39 | 2.93 ± 1.72 | 2.08 ± 0.37 | NS |
| Glucose mmol/L | 5.10 ± 0.43 | 5.41 ± 0.88 | 4.98 ± 1.13 | NS |
| AspAt U/L | 26.13 ± 5.08 | 32.71 ± 16.75 | 36.00 ± 4.85 | 0.048 * |
| ALT U/L | 38.75 ± 20.71 | 76.86 ± 61.65 | 52.00 ± 23.00 | NS |
| Aldosteron pg/mL | 97.70 ± 53.77 | 145.36 ± 135.00 | 135.02 ± 138.60 | NS |
SDMA: Symmetric Dimethylarginine, Cyst C: Cystatin C, Mg: magnesium, Na: sodium, K: potassium, Cl: chlorine, Ca2+: ionized calcium, Fe: iron, CRP: C-reactive protein, AspAT: aspartate transaminase, ALT: alanine transaminase. * Statistically significant differences between the control group and kidney group, # statistically significant differences between the heart and the kidney group, ^ statistically significant differences between the healthy and the heart group, NS: statistically nonsignificant.