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. 2019 Aug 30;24(17):3161. doi: 10.3390/molecules24173161

Figure 8.

Figure 8

The metabolic pathway networks of particularly significant potential biomarkers for the therapeutic effect of p-b4 on MSU crystal-induced GA rats. The word in blue ovals means enzyme according to KEGG pathway database; the word in red and green rectangles means the sampling time of serum; red indicates an up-regulation of metabolites and green indicates a down-regulation of metabolites (GA model group VS P-b4 group); * means p < 0.05, ** means p < 0.01.