Table 2.
Logistic regression model with predictors of unfavorable outcome (N = 259)
| Characteristics | Unadjusted OR (95% CI) | p Value | Adjusted OR (95% CI) | p Value |
|---|---|---|---|---|
| Age (years) | 1.029 (1.001–1.057) | .041 | — | — |
| Male no. (%) | 0.875 (0.511–1.499) | .627 | — | — |
| SBP (mmHg) | 1.005 (0.994–1.017) | .358 | — | — |
| DBP (mmHg) | 1.005 (0.985–1.025) | .616 | — | — |
| Hypertension no. (%) | 1.936 (0.907–4.131) | .088 | — | — |
| Hyperlipidemia no. (%) | 0.881 (0.493–1.573) | .668 | — | — |
| Diabetes no. (%) | 1.914 (1.115–3.285) | .019 | — | — |
| CAD no. (%) | 1.967 (0.994–3.894) | .052 | — | — |
| Smoking no. (%) | 1.094 (0.651–1.838) | .733 | — | — |
| Alcohol drinking no. (%) | 0.833 (0.467–1.483) | .534 | — | — |
| BMI (kg/m2) | 0.929 (0.850–1.015) | .104 | — | — |
| Infract volume (cm3) | 1.036 (1.003–1.071) | .032 | — | — |
| Location of cerebral infarction no. (%) | 1.268 (0.950–1.693) | .107 | — | — |
| Hospital stays (days) | 1.111 (1.033–1.196) | .005 | — | — |
| NIHSS score on admission, median (IQR) | 1.374 (1.238–1.525) | <.001 | 1.476 (1.117–1.949) | .006 |
| NIHSS score at discharge, median (IQR) | 1.381 (1.236–1.543) | <.001 | — | — |
| Laboratory tests | — | — | — | — |
| WBC (109/L) | 1.083 (0.958–1.225) | .202 | — | — |
| Neutrophils (109/L) | 1.160 (1.005–1.338) | .043 | — | — |
| ALT (IU/L) | 0.985 (0.964–1.007) | .171 | — | — |
| AST (IU/L) | 1.008 (0.985–1.031) | .495 | — | — |
| LDL‐C (mmol/L) | 1.137 (0.852–1.517) | .383 | — | — |
| TC (mmol/L) | 1.010 (0.799–1.277) | .933 | — | — |
| TG (mmol/L) | 0.707 (0.519–0.963) | .028 | 0.628 (0.400–0.986) | .043 |
| HbA1c (%) | 1.200 (1.024–1.407) | .025 | — | — |
| Albumin (g/L) | 0.919 (0.855–0.989) | .024 | — | — |
| SCr (μmol/L) | 1.001 (0.989–1.013) | .867 | — | — |
| BUN (mmol/L) | 1.040 (0.881–1.228) | .642 | — | — |
| Uric acid (mmol/L) | 0.997 (0.994–1.000) | .028 | — | — |
| Hs‐CRP (mg/L) | 1.072 (1.031–1.114) | <.001 | 1.052 (1.010–1.096) | .016 |
| IL‐33 (ng/ml) | 0.973 (0.960–0.987) | <.001 | 0.956 (0.937–0.976) | <.001 |
| Medications no. (%) | — | — | — | — |
| Antiplatelet agents | 0.501 (0.288–0.872) | .015 | — | — |
| Anticoagulation agents | 2.012 (0.629–6.433) | .238 | — | — |
| Statins | 0.551 (0.308–0.987) | .045 | — | — |
Abbreviations: ALT, alanine aminotransferase; AST, aspartate transaminase; BMI, body mass index; BUN, blood urea nitrogen; CAD, coronary artery disease; CI, confidence interval; DBP, diastolic blood pressure; HbA1c, glycosylated hemoglobin; Hs‐CRP, high‐sensitivity C‐reactive protein; IL‐33, interleukin‐33; IQR, interquartile range; LDL‐C, low‐density cholesterol; NIHSS, National Institutes of Health Stroke Scale; R, odds ratio; SBP, systolic blood pressure; SCr, serum creatinine; TC, total cholesterol; TG, triglycerides; WBC, leukocyte.