Table 2.
Risk factor analysis for pre-PCI brain metastasis
| Covariates | Univariate | Multivariate | ||
|---|---|---|---|---|
| RR (95% CI) | P | RR (95% CI) | P | |
| Age at diagnosis | 0.976 (0.924–1.032) | 0.400 | ||
| Gender | 0.510 (0.107–2.437) | 0.399 | ||
| Smoking | 3.781 (0.822–17.400) | 0.088 | 4.376 (0.895–21.394) | 0.068 |
| T stage (1–2 vs 3–4) | 1.383 (0.546–3.502) | 0.494 | 1.099 (0.411–2.941) | 0.851 |
| N stage (0–2 vs 3) | 1.458 (0.499–4.259) | 0.490 | 1.389 (0.456–4.235) | 0.564 |
| CRT-D (months) | 1.340 (0.981–1.831) | 0.066 | 1.406 (1.007–1.964) | 0.045* |
Abbreviation: PCI Prophylactic cranial irradiation, RR Risk ratio, CI Confidence interval, CRT-D Chemoradiotherapy duration. Age and CRT-D as continuous variables. Binary logistic regression was employed for analysis. (*) statistically significant