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. 2019 Sep 18;9:75. doi: 10.1186/s13578-019-0340-9

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — SMYD2 depletion obviously restrained the proliferation of cervical cancer cells. a Representive images showed the results of colony formation assays of Caski and Siha cells that were transfected with control or SMYD2 shRNA. Cultivation lasted 2 weeks. b MTT assays showed the difference between control and SMYD2 knockdown cervical cancer cells. c Immunoblot assay revealed the markedly decreased expression of SMYD2 in both Caski and Siha cells. d Immunoblot assay showed the PCNA expression was obviously down-regulated in 2 types of cervical cancer cells. Results are presented as mean ± SD, *P < 0.05