Table 2.
Describing the serological and Doppler findings according to various types of classification
| Investigations | VSCS | Clinical classification | Etiological classification | ||||||
|---|---|---|---|---|---|---|---|---|---|
| VSCS (≥5) 24 (100%) | VSCS (1-4) 26 (100%) | P | C4a-C6 21 (100%) | C0-C3 29 (100%) | P | Primary 36 (100%) | No venous etiology 14 (100%) | P | |
| Blood investigations | |||||||||
| Homocysteine (high) | 10 (42) | 6 (23) | 0.16 | 7 (33) | 9 (31) | 0.86 | 12 (33) | 4 (29) | 0.75 |
| D-dimer (high) | 6 (26) | 4 (15) | 0.35 | 5 (25) | 5 (17) | 0.51 | 8 (23) | 2 (14) | 0.50 |
| Factor V (+) | 4 (17) | 0 | 0.03 | 4 (19) | 0 | 0.01 | 4 (11) | 0 | 0.19 |
| Total cholesterol (high) | 5 (21) | 7 (21) | 0.61 | 5 (24) | 7 (24) | 0.98 | 8 (22) | 4 (29) | 0.64 |
| Total TG (high) | 10 (42) | 8 (31) | 0.42 | 8 (38) | 10 (35) | 0.79 | 14 (39) | 4 (29) | 0.50 |
| HDL (low) | 8 (33) | 7 (27) | 0.62 | 6 (29) | 9 (31) | 0.85 | 9 (25) | 6 (43) | 0.22 |
| VLDL (high) | 3 (13) | 1 (4) | 0.26 | 1 (5) | 3 (10) | 0.47 | 3 (8) | 1 (7) | 0.89 |
| LDL (high) | 5 (12) | 5 (19) | 0.89 | 4 (19) | 6 (21) | 0.89 | 6 (17) | 4 (29) | 0.35 |
| TG/HDL ratio (high) | 11 (46) | 9 (35) | 0.42 | 10 (48) | 10 (34) | 0.35 | 16 (44) | 4 (29) | 0.30 |
| Doppler findings | |||||||||
| Perforators (+) | 21 (88) | 15 (58) | 0.02 | 20 (95) | 16 (55) | 0.002 | 35 (97) | 1 (7) | <0.0001 |
| Great saphenous vein (+) | 11 (46) | 8 (31) | 0.27 | 13 (62) | 6 (21) | 0.003 | 18 (50) | 1 (7) | 0.005 |
| Varicosities (+) | 16 (67) | 7 (27) | 0.005 | 15 (71) | 8 (28) | 0.002 | 23 (64) | 0 | <0.0001 |
| Thrombosis (+) | 2 (8) | 0 | 0.13 | 2 (10) | 0 | 0.09 | 2 (6) | 0 | 0.37 |
HDL: High-density lipoprotein, LDL: Low-density lipoprotein, VLDL: Very low-density lipoprotein, TG: Triglycerides, VSCS: Venous Severity Clinical Score