TABLE 2.
Time Trend in 1-Year and 5-Year All-Cause Mortality in Patients With a First Hospital Admission for Crohn’s Disease in the Netherlands Between 1998 and 2010, Stratified by Sex and Age
| 1-y All-Cause Mortality | 5-y All-Cause Mortality | |||||
|---|---|---|---|---|---|---|
| 1998–2004, % | 2005–2010, % | Adjusted HR (95% CI) | 1998–2004, % | 2005–2010, % | Adjusted HR (95% CI) | |
| Men | ||||||
| 0–19 y | 0 | 0 | - | 0.3 | 1.9 | 5.90 (0.65–53.9) |
| 20–39 y | 0.7 | 0.5 | 0.89 (0.25–3.21) | 1.7 | 2.1 | 1.23 (0.54–2.84) |
| 40–59 y | 3.0 | 2.1 | 0.64 (0.33–1.26) | 7.1 | 5.4 | 0.70 (0.43–1.14) |
| 60–79 y | 16.4 | 12.0 | 0.69 (0.48–1.00) | 33.9 | 27.7 | 0.77 (0.59–1.02) |
| ≥80 y | 30.4 | 38.5 | 1.32 (0.79–2.21) | 76.1 | 70.1 | 0.93 (0.65–1.35) |
| Total | 4.9 | 4.4 | 0.81 (0.62–1.06) | 11.3 | 10.5 | 0.83 (0.69–1.01) |
| Women | ||||||
| 0–19 y | 0 | 0 | - | 0 | 0 | - |
| 20–39 y | 0.6 | 0.3 | 0.67 (0.19–2.31) | 1.6 | 0.8 | 0.51 (0.22–1.21) |
| 40–59 y | 2.9 | 1.7 | 0.62 (0.34–1.12) | 7.0 | 5.4 | 0.78 (0.52–1.15) |
| 60–79 y | 10.8 | 9.8 | 0.90 (0.63–1.29) | 28.8 | 24.8 | 0.79 (0.61–1.01) |
| ≥80 y | 28.7 | 23.4 | 0.73 (0.47–1.13) | 67.3 | 62.3 | 0.77 (0.57–1.05) |
| Total | 4.1 | 3.4 | 0.76 (0.59–0.96) | 10.6 | 9.5 | 0.75 (0.63–0.89) |
Hazard ratios are adjusted for age, marital status, ethnic origin, and the Charlson comorbidity index.27
Abbreviations: CI, confidence interval; HR, hazard ratio.