Appendix Table 3.

Number at risk, number of deaths, distribution of VACS Index 2.0 scores, and all-cause mortality hazard ratio (HR) per 5 points, in the development sample (VACS) and validation sample (ART-CC), overall and by individual cohort (A-I).

			VACS Index 2.0 Score					Risk of all-cause mortality, per 5 points
	N	Deaths	Median	25th	75th	1st	99th	HR (95% CI)
VACS	28,390	7,293	51	39	66	15	111	1.31 (1.30-1.31)
ART-CC	12,109	722	41	33	52	14	97	1.37 (1.35-1.39)
A	1,011	40	41	31	52	14	91	1.41 (1.32-1.52)
B	944	95	42	34	53	17	98	1.38 (1.31-1.44)
C	1,872	112	35	27	46	11	93	1.37 (1.32-1.42)
D	1,509	78	44	36	54	18	89	1.38 (1.31-1.45)
E	863	73	42	33	54	15	104	1.34 (1.28-1.41)
F	1,899	111	42	34	53	17	102	1.38 (1.33-1.43)
G	2,231	120	42	34	54	16	94	1.40 (1.34-1.46)
H	891	53	44	34	54	19	103	1.34 (1.27-1.42)
I	889	40	41	33	50	17	95	1.40 (1.30-1.51)