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. Author manuscript; available in PMC: 2020 May 8.
Published in final edited form as: Cell Host Microbe. 2019 Apr 23;25(5):656–667.e8. doi: 10.1016/j.chom.2019.03.007

Table 1 |.

Estimation of the number of mutations occurring daily within the human microbiome

Number of Bacteria
(cells/microbiome)
(Sender et al., 2016)		 Mutation rate
(SNP/nucleotide/replication)
(Barrick and Lenski 2013)		 Bacterial genome
Size
(nucleotide/cell)
(Nayfach and
Pollard 2015)		 Range of
replication rate
(replication/day)
(Korem et al.,
2015)		 → Estimated number of
de novo mutations
(SNP/microbiome/day)
1013 −1014 10−10 −10−9 2–6×106 1–10 2×109 – 6×1012