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Effect of atabrine on the neutrophil counts in the blood of subjects dosed with plasmochin with or without atabrinea
| Treatment | No. of subjects | Avg no. of neutrophils/ml |
% decrease in neutrophils | |
|---|---|---|---|---|
| Prior to dosing | After 14 days of dosing | |||
| Plasmochin | ||||
| 30 mg | 11 | 4,650 | 2,890 | 38 |
| 60 mg | 4 | 3,878 | 2,920 | 25 |
| 90 mg | 12 | 4,762 | 1,714 | 64 |
| 30 mg plasmochin + atabrine | 6 | 5,093 | 1,493 | 69 |
Adapted from reference 151 with permission of the American Society for Clinical Investigation.
