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MA-induced [125I]RTI-55 saturation binding in synaptosomes. Taar1 WT and KO mice received four intraperitoneal injections of saline or MA (5 mg/kg), 2 hours apart, and were euthanized 24 hours following the final injection. Values were normalized to the amount of protein in each sample. Experiments were conducted as described in text. Shown is a representative saturation curve. Inset: Scatchard transformation of [125I]RTI-55 binding data.
