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. 2019 Oct;371(1):36–44. doi: 10.1124/jpet.119.258970

TABLE 3.

[125I]RTI-55 binding in synaptosomes

Data represent mean ± S.E.M. for each genotype and treatment group from four independent experiments, n = 4 mice per genotype per treatment group.

Treatment Genotype Bmax S.E.M. Kd ± S.E.M.
pmol/mg protein nM
Saline Taar1 WT 10.3 ± 0.8 3.7 ± 0.2
Taar1 KO 11.7 ± 1.3 4.3 ± 0.4
MA Taar1 WT 8.5 ± 0.4* 3.6 ± 0.4
Taar1 KO 7.6 ± 1.0* 3.8 ± 0.7
*

P < 0.01 compared with saline treatment (main effect).