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Terminal liver concentrations of DCF, OH-DCF, and DCF-AG in FVB WT and FVB Mrp3 KO mice after 3- (A) or 10-mg/kg-DCF dose (B). Hepatic concentrations of DCF, OH-DCF, and DCF-AG in KO (□) and WT (■) mice were determined 90 minutes after DCF administration. Data are expressed as the mean ± S.E.M. for six to seven subjects/group.
