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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: Am J Hematol. 2018 Sep 26;93(10):1245–1253. doi: 10.1002/ajh.25234

Table 2.

Prognostic score for patients with intermediate risk myelodysplastic syndrome (0–4 score).

Variable Coefficient HR (95% CI) p Score No. Patients
* Age ≥ 66 years
 No 0 143
 Yes 0.87 2.43 (1.74–3.38) <0.001 2 152
* Peripheral blood blasts ≥ 2%
 No 0 247
 Yes 0.52 1.69 (1.14–2.50) 0.009 1 48
Red blood cell transfusion
 No 0 199
 Yes 0.51 1.66 (1.18–2.32) 0.003 1 96

Score were obtained by dividing each coefficient by 0.51 (smallest coefficient) and rounding each results to the nearest integer and changing the results to the absolute value.

*

Based on CART. CART = Classification and Regression Tree analysis. CART analysis for failure time data uses the martingale residuals of a Cox model to calculate (approximate) chi-square values for all possible cut point on all the CART covariates. Coefficient, HR, and p are given for reduced model using backward elimination methods as described. Complete univariate and multivariate analysis are included in supplemental Table S