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. Author manuscript; available in PMC: 2019 Oct 8.
Published in final edited form as: Nat Metab. 2019 Apr 8;1(4):475–484. doi: 10.1038/s42255-019-0051-x

Fig. 3.

Fig. 3

Leptin-responsive transcriptome. a A heatmap of mean subtracted, log stabilized read counts showing differentially expressed genes for fasted mice treated either with saline (SSS) or with leptin at 12, 24 and 34 hours (LLL). b Boxplots showing the expression levels of Etv6, Socs3 and Gucy2c in LepRb GFP-positive (green) or negative (grey) nuclei within the two conditions. The y-axis shows stabilized expression which is log2 scale for sequencing depth normalized counts determined by DESeq239. Box plots represent 25th to 75th percentiles and the midline indicates the median. n=3 biologically independent replicates.