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. Author manuscript; available in PMC: 2019 Sep 18.
Published in final edited form as: Cell Rep. 2019 Aug 20;28(8):2037–2047.e4. doi: 10.1016/j.celrep.2019.07.061

Figure 6. miR-216a Gain of Function Impairs β-Catenin Accumulation in MG after Intense Light Damage.

Figure 6.

(A) Control miRNA or miR-216a was injected and electroporated into the left eyes of wild-type zebrafish before intense light exposure (0 h). After 45 h, retinas were collected, sectioned, and immunostained using antibodies against β-catenin (red) and PCNA (green). Nuclei were counterstained with TOPRO (blue).

(B) β-Catenin colocalized with PCNA+ proliferating MG after 45 h of intense light damage. β-Catenin accumulation was not detected in miR-216a-over-expressing retinas. Scale bar, 50 µm.