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. 2019 Sep 18;14(9):e0221709. doi: 10.1371/journal.pone.0221709

Table 3. Expected number of events, costs, and cost per additional outcome avoided (Toxoscreen project).

Assessment period Prenatal screening (a) Neonatal screening (b) Difference (b–a)
Short term assessment (1 year) Outcomes per 1000 women/children
Strictly toxoplasmosis-related events (STRE)
Live-born children with toxoplasmosis (1) 0.332 0.660 0.328
Toxoplasmosis-related fetal losses and neonatal deaths (2) 0.002 0.007 0.005
Total STRE (= 1+2) 0.334 0.667 0.333
Global events (GE)
Total GE (= STRE+ neonatal deaths, fetal losses unrelated to toxoplasmosis + abortion and fetal losses due to amniocentesis) 156.033 161.272 5.239
Mean cost per woman/child (€) 851 773 -78
Cost per additional outcome avoided
 STRE 232 631.4
 GE 14 826.0
Long term assessment (15 years) Outcomes per 1000 women/children
15 years–STRE
Sequelae 0.031 0.067 0.036
Total STRE (sequelae+(2)) 0.033 0.075 0.042
15 years–GE (15 years STRE + neonatal deaths, fetal losses unrelated to toxoplasmosis + abortion and fetal losses due to amniocentesis) 155.240 158.748 3.508
Mean cost (€) 826 751 -75
Cost per additional outcome avoided
 STRE 1 795 145
 GE 21 472

(a) Reference strategy