Table 3. Expected number of events, costs, and cost per additional outcome avoided (Toxoscreen project).
Assessment period | Prenatal screening (a) | Neonatal screening (b) | Difference (b–a) |
---|---|---|---|
Short term assessment (1 year) | Outcomes per 1000 women/children | ||
Strictly toxoplasmosis-related events (STRE) | |||
Live-born children with toxoplasmosis (1) | 0.332 | 0.660 | 0.328 |
Toxoplasmosis-related fetal losses and neonatal deaths (2) | 0.002 | 0.007 | 0.005 |
Total STRE (= 1+2) | 0.334 | 0.667 | 0.333 |
Global events (GE) | |||
Total GE (= STRE+ neonatal deaths, fetal losses unrelated to toxoplasmosis + abortion and fetal losses due to amniocentesis) | 156.033 | 161.272 | 5.239 |
Mean cost per woman/child (€) | 851 | 773 | -78 |
Cost per additional outcome avoided | |||
STRE | 232 631.4 | ||
GE | 14 826.0 | ||
Long term assessment (15 years) | Outcomes per 1000 women/children | ||
15 years–STRE | |||
Sequelae | 0.031 | 0.067 | 0.036 |
Total STRE (sequelae+(2)) | 0.033 | 0.075 | 0.042 |
15 years–GE (15 years STRE + neonatal deaths, fetal losses unrelated to toxoplasmosis + abortion and fetal losses due to amniocentesis) | 155.240 | 158.748 | 3.508 |
Mean cost (€) | 826 | 751 | -75 |
Cost per additional outcome avoided | |||
STRE | 1 795 145 | ||
GE | 21 472 |
(a) Reference strategy