Table 1. Parameter values.
Parameter | Description | Value | Source |
---|---|---|---|
sT | Source terms of CD4+ T cells from thymus | 10cellsd−1 | [48] |
K | Carrying capacity of CD4+ T cells | 1500 cells ml−1 | Est. |
μ | Proportion of infected cells that die per time step | 0.5 to 1 | [33] |
γ | Growth rate of CD4+ T cells | 2.7 cells d−1 | Est. |
β1 | Virus infectivity | 2.4 × 10−5 ml−1 d−1 | [33] |
β2 | Cell-associated virus infectivity | 100 − 1000 × β1 | [6, 8, 53] |
ϕ | Virus production/provirus/cycle | 1000 virions | [29] |
θ1 | Transition Probability | [33] | |
θ2 | Transition Probability | 0.06315 | [48] |
θ3 | Probability of surviving and remaining in provirus stages | 0.43685 | [48] |
Est. means that parameters were estimated/derived to simulate acceptable HIV dynamics.