Table 2. Top 10 up-regulated and down-regulated genes in non-MSL TN-IBC versus non-MSL TN-non-IBCa.
| Up-regulated in TN-IBC | Down-regulated in TN-IBC | ||
|---|---|---|---|
| Molecule | Log ratio | Molecule | Log ratio |
| Vanderbilt | |||
| *PADI3 | 0.604 | SERPINE2 | -0.941 |
| ARF6 | 0.574 | CNN3 | -0.836 |
| *MCTP1 | 0.551 | *CDC42EP3 | -0.622 |
| TFPI | 0.471 | NME7 | -0.535 |
| ZFP36 | 0.399 | *SSR1 | -0.528 |
| CLEC1A | 0.351 | SSR3 | -0.527 |
| PAK4 | 0.344 | *RSBN1 | -0.466 |
| NOTCH4 | 0.309 | SNRNP40 | -0.461 |
| EFCC1 | 0.298 | CRK | -0.443 |
| PLXND1 | 0.282 | *ZC3H13 | -0.442 |
| TNBCtype | |||
| *PADI3 | 0.750 | *CDC42EP3 | -0.752 |
| *MCTP1 | 0.675 | LOC730101 | -0.682 |
| TCF4 | 0.671 | *SSR1 | -0.652 |
| RPL37A | 0.670 | TARDBP | -0.609 |
| COA1 | 0.647 | *ZC3H13 | -0.609 |
| MICAL2 | 0.558 | PRKD3 | -0.584 |
| FPR1 | 0.538 | KDM3B | -0.559 |
| LPIN2 | 0.496 | COPG1 | -0.551 |
| MERTK | 0.439 | *RSBN1 | -0.548 |
| MAPKAPK3 | 0.364 | DOPEY1 | -0.510 |
a Results are based on 75 differentially expressed genes identified in the analysis based on the Vanderbilt classification and 81 differentially expressed genes identified in the analysis based on Insight TNBCtype.
* Genes that were differentially regulated in both the Vanderbilt and Insight TNBCtype analyses.