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. 2019 Sep 18;14(9):e0222485. doi: 10.1371/journal.pone.0222485

Table 5. Means, standard deviations and effect sizes of primary and secondary outcomes.

Unadjusted mean (standard deviation) {valid n} Effect size; p-value
Pre-treatment Post-treatment 3-month f/up 12-month f/up Within-group Within-group Between-group Within-group Within-group
pre to post pre to f/up ICBT vs. WL post to 3 f/up 3 to 12 f/up
ADIS CSRprim
ICBT 6.69 (0.68) {35} 3.83 (2.65) {35} 3.88 (2.56) {33} d = 1.48, p < .001 d = 1.50, p < .001a d = .65, p = .022 d = -.02, p = .495
WL 6.54 (0.92) {35} 5.09 (2.29) {32} d = .83, p = .001
ADIS CSRall
ICBT 13.17 (5.28) {35} 6.89 (4.56) {35} 6.39 (4.64) {33} d = 1.27, p < .001 d = 1.36, p < .001a d = .83, p = .002 d = .11, p = .482
WL 11.17 (4.42) {35} 9.28 (4.13) {32} d = .44, p = .012
SCAS-Cadol
ICBT 47.29 (15.38) {35} 31.88 (16.06) {32} 28.74 (16.08) {27} 33.36 (12.64) {25} d = .98, p < .001 d = .99, p < .001b d = .68, p < .001 d = .20, p = .054 d = -.32, p = .056
WL 45.60 (15.79) {35} 40.19 (19.90) {31} d = .30, p = .038
SCAS-Pmother
ICBT 48.23 (17.28) {35} 29.43 (13.60) {35} 28.73 (16.57) {33} 28.58 (18.58) {31} d = 1.21, p < .001 d = 1.10, p < .001b d = 1.12, p < .001 d = .05, p = .548 d = .01, p = .849
WL 42.71 (14.85) {35} 41.31 (17.54) {32} d = .09, p = .632
SCAS-Pfather
ICBT 41.45 (19.18) {31} 32.46 (17.29) {26} 28.33 (15.33) {24} 23.55 (18.77) {22} d = .49, p = .001 d = .94, p < .001b d = .46, p = .011 d = .25, p = .007 d = .28, p = .484
WL 37.41 (12.75) {32} 36.96 (14.35) {27} d = .03, p = .579
CALISadol
ICBT 13.54 (6.56) {35} 10.59 (7.65) {32} 8.93 (7.63) {27} 9.72 (8.55) {25} d = .41, p = .007 d = .50, p = .002b d = .21, p = .254 d = .22, p = .183 d = -.10, p = .663
WL 13.97 (6.73) {35} 12.42 (8.65) {31} d = .20, p = .180
CALISmother
ICBT 32.14 (11.36) {35} 22.49 (12.67) {35} 23.21 (16.33) {33} 20.61 (14.96) {31} d = .80, p < .001 d = .87, p < .001b d = .93, p < .001 d = -.05, p = .856 d = .17, p = .450
WL 33.71 (11.91) {35} 35.34 (13.47) {32} d = -.13, p = .513
CALISfather
ICBT 29.42 (14.07) {31} 25.89 (15.58) {27} 24.21 (14.53) {24} 16.59 (13.50) {22} d = .24, p = .049 d = .93, p < .001b d = .20, p = .227 d = .11, p = .195 d = .54, p = .044
WL 28.91 (9.74) {32} 28.52 (13.00) {27} d = .03, p = .574
WHO-5
ICBT 44.69 (21.44) {35} 49.50 (21.69) {32} 55.85 (25.21) {27} 48.48 (25.98) {25} d = .22, p = .143 d = .16, p = .129b d = -.04, p = .945 d = .27, p = .100 d = -.29, p = .105
WL 48.91 (19.19) {35} 54.06 (20.39) {31} d = .26, p = .135
S-MFQadolescent
ICBT 10.46 (6.47) {35} 8.06 (7.77) {32} d = .34, p = .014 d = -.11, p = .932
WL 10.94 (7.07) {35} 7.77 (7.14) {31} d = .45, p = .010
S-MFQmother
ICBT 9.91 (5.79) {35} 5.77 (5.25) {35} d = .75, p < .001 d = .60, p = .008
WL 10.43 (6.15) {35} 9.47 (6.37) {32} d = .15, p = .360
S-MFQfather
ICBT 8.26 (5.43) {31} 7.15 (5.86) {27} d = .20, p = .103 d = .07, p = .813
WL 7.88 (4.89) {32} 6.56 (4.85) {27} d = .27, p = .229
SEQ-Ctotal
ICBT 70.71 (13.88) {35} 75.25 (16.55) {32} d = .30, p = .008 d = .12, p = .367
WL 71.23 (15.76) {35} 74.00 (16.27) {31} d = .17, p = .174
SEQ-Cacademic
ICBT 27.17 (7.14) {35} 27.13 (8.04) {32} d = -.01, p = .970 d = -.08, p = .449
WL 26.11 (8.49) {35} 26.71 (7.84) {31} d = .07, p = .270
SEQ-Csocial
ICBT 25.09 (5.46) {35} 26.06 (6.11) {32} d = .17, p = .133 d = .04, p = .668
WL 26.20 (6.79) {35} 27.06 (6.32) {31} d = .13, p = .412
SEQ-Cemotional
ICBT 18.46 (5.92) {35} 22.06 (5.87) {32} d = .61, p < .001 d = .38, p = .026
WL 18.91 (5.26) {35} 20.23 (6.35) {31} d = .23, p = .205

Note. ADIS: Anxiety Disorder Interview Schedule for DSM-IV; CSR: Clinical Severity Rating; SCAS-C/P: Spence Children’s Anxiety Scale Child/Parent version; CALIS: Child Anxiety Life Inference Scale; WHO-5: WHO-5 Well-being Index Questionnaire; S-MFQ: short version of the Moods and Feelings Questionnaire; SEQ-C: The Self-Efficacy Questionnaire for Children; f/up: follow-up.

a Pre to 3-month follow-up

b Pre to 12-month follow-up. For the SCAS, CALIS and S-MFQ, a family-wise Bonferroni-corrected significance level of p = 0.017 was deployed. Effect size calculations based on observed values and expressed as Cohen’s d. Positive effect sizes indicate improvement.