. Author manuscript; available in PMC: 2020 Sep 1.

Published in final edited form as: Eur J Pharm Biopharm. 2019 Aug 6;142:543–552. doi: 10.1016/j.ejpb.2019.08.004

Table 4.

Calculated and observed bacterial survival rate of P. aeruginosa strains FADD1-PA001 or JIP 865 of co-spray dried PEV20-ciprofloxacin formulation A and B before and after unit dose test using low and high resistance Osmohaler™ (n=6).

			Low resistance		High resistance
Strains	Formulations	Unit dose test	Calculated	Observed	Calculated	Observed
FADD1-PA001			0.2±0.06		0.06±0.03
	A	Before		0.04±0.001^*		0.005±0.0008^*
		After		0.05±0.002^*		0.006±0.0003^*
	B	Before		0.04±0.002^*		0.004±0.0022^*
		After		0.04±0.002^*		0.0004±0.0002^*
JIP 865			0.6±0.2		0.6±0.08
	A	Before		0.07±0.006^*		0.02±0.002^*
		After		0.08±0.007^*		0.02±0.005^*
	B	Before		0.08±0.009^*		0.02±0.001^*
		After		0.07±0.01^*		0.02±0.002^*

Statistically significant (p<0.05) according to Student’s t-test.