Figure 1.
The effect of IL-6 on skeletal muscle mitochondrial function. Tibialis anterior (TA) respiratory control ratio (n=4 per group). Values are means plus / minus standard deviation (SD). A) 0.25mM of ADP was injected into the chamber to induce STATE 3 respiration for a duration of 5 minutes. B) 10ug/mL of Oligomycin was injected to induce steady STATE 4 respiration for a duration of 10 minutes. C) Respiratory Control Ratio (RCR) was calculated by dividing STATE 3 by STATE 4 respirations. & Significantly different from all groups. Significance was set at p<0.05. Two-Way ANOVA.