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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Environ Int. 2019 Jul 18;131:104993. doi: 10.1016/j.envint.2019.104993

Table 3. Association of Umixor Bmixmetals indices with renal parameters.

Results of WQS regression analysis per renal outcome for the urine and blood mixtures (Umix and Bmix). Parameter estimates (βWQS), 95% confidence intervals (CI), and p-values of the WQS mixture reported for each model. Component weights reported as percentages for mixtures with significant effects (n/a: not applicable).

Mixture Outcome WQS Mixture result Component Weights
Umix BUN 0.0159 (0.005, 0.027) p = 0.006 As
Pb
Hg
Cd		 72%
14%
11%
3%
eGFR 0.0137 (0.007, 0.020) p <0.0001 Hg
Cd
As
Pb		 61%
17%
13%
9%
SUA −0.0073 (−0.017, 0.002) p = 0.130 n/a
SBP −0.0007 (−0.005, 0.003) p = 0.710 n/a
Urine albumin 0.0731 (0.024, 0.123) p = 0.004 Cd
Hg
Pb
As		 37%
33%
25%
6%
Bmix BUN 0.0040 (−0.003, 0.011) p = 0.265 n/a
eGFR −0.0032 (−0.009, 0.002) p = 0.241 n/a
SUA 0.0063 (0.000, 0.013) p = 0.052 Pb
Hg
Cd		 43%
33%
24%
SBP 0.0010 (−0.001,0.003) p = 0.338 n/a
Urine albumin 0.0035 (−0.025, 0.031) p = 0.807 n/a