Table 1. H₁R Binding of Rupatadine and Desloratadine Analogues^c.

^aFumarate salt.

^bPreviously reported (see text for references).

^cBinding affinity (pK_i) values were determined by competition binding experiments using [³H]mepyramine, and KRI values were determined by dual-point competition association experiments using [³H]levocetirizine. Depicted values represent the mean ± standard error of the mean (SEM) of ≥3 experiments